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| Osteoarthritis is caused by the breakdown of cartilage. Cartilage is the tough elastic material that covers and protects the ends of bones. Bits of cartilage may break off and cause pain and swelling in the joint between bones. This pain and swelling is called inflammation. Over time the cartilage may wear away entirely, and the bones will rub together. Osteoarthritis can affect any joint but usually affects hips, knees, hands and spine. Learn More | |