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Painful joints can raise many questions.

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What happens inside a joint?
What is hyaluronic acid?

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And what does treatment with Crespine
Gel involve? Let us take a closer look.

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In the knee, the thigh bone meets the shin bone.

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Cartilage covers the joint surfaces.

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The joint also contains synovial fluid.
This helps reduce friction during movement.

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Hyaluronic acid is a natural
component of this fluid.

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Hyaluronic acid consists of long
molecular chains and can bind water.

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It contributes to the elastic and
lubricating properties of synovial fluid.

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In this way, the fluid supports
movement within the joint.

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In osteoarthritis, cartilage and other
tissues within the joint change. Symptoms

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can have different causes. That is why a
medical assessment comes before treatment.

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Crespine Gel is a gel implant made from
cross-linked hyaluronic acid of non-animal

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origin. Cross-linked means that the
molecular chains are joined together.

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Another product variant is Crespine Gel Plus.

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It also contains prilocaine,
a local anaesthetic.

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Crespine Gel supplements the synovial
fluid that has changed in osteoarthritis.

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The aim of treatment is to relieve
pain and improve joint function.

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Crespine Gel is intended for a single injection.

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Crespine Gel is injected into
the joint space by a qualified

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healthcare professional. Whether it
is suitable is assessed individually.

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This includes the diagnosis,
contraindications and other treatment options.

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Ask your doctor about the expected
benefits, risks and alternatives.

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Possible risks include pain,
swelling and a joint infection.

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Crespine Gel. This information
does not replace medical advice.

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Discuss your symptoms and
treatment options with your doctor.