WEBVTT

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High molecular weight,
cross-linked, or non-animal origin.

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When you read about hyaluronic acid,
you may come across many terms.

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They describe different properties.
This video explains four of them:

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molecular size, cross-linking,
concentration and origin.

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Hyaluronic acid consists of long
chains of repeating building blocks.

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Put simply, molecular weight
describes how large these chains are.

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High molecular weight means the chains
are relatively large. Low molecular weight

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means they are smaller. So this term
refers to the size of individual molecules.

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The second question is whether there are
additional connections between the chains.

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Non-cross-linked hyaluronic acid does
not have these extra connections.

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In cross-linked hyaluronic acid,
connections are added between the chains.

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This can change the properties of the material.

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Cross-linked is therefore not another
word for high molecular weight.

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Another measurement is concentration.
It describes how much hyaluronic

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acid is present in a given amount of
fluid, such as one millilitre. Two products

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can have the same concentration but still
differ in molecular size or cross-linking.

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The source is also often mentioned.

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Hyaluronic acid can be produced by
fermentation using microorganisms. Other

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products use materials of animal origin.
This information describes production.

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On its own, it does not tell you which
product is suitable for a particular person.

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The four measurements complement each other.

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A high concentration does not
automatically mean more cross-linking.

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And a particular material property
does not, on its own, prove

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a greater benefit for symptoms. Suitable
clinical studies are needed to assess that.

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Treatment cannot be chosen
from material terms alone.

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Discuss the expected benefits, possible
risks and alternatives with your doctor.

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Crespine Gel is a gel implant made from
cross-linked hyaluronic acid of non-animal

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origin. Cross-linked means that the
molecular chains are joined together.

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Another product variant is Crespine Gel Plus.

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It also contains prilocaine,
a local anaesthetic.

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Crespine Gel. This information
does not replace medical advice.

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Discuss your symptoms and
treatment options with your doctor.